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Hi mate,
It is fairly common for some snakes to go off their food prior to shedding. Your description of loose skin around the front area would indicate that it is indeed about to shed in the next week or so. You really shouldn't be too concerned about pythons not eating unless a month or so has passed as a ung animal or a few months as an adult animal. My female coastal often goes 4-6 weeks between feeds.
Obviously, if the situation continues over a month or so it would be a good idea to chat to your local VET about it!
Cheers,
Davo
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