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It seems clear that the 'defective' gene that produces a Jag also causes these neurological problems in a small number of offspring, it doesn't appear to be related to line breeding as it was found even when outcrossed.
It can't be found in any lookalikes as they don't have the Jag gene.
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"If you know everything you may as well blow your brains out because the reason for existence is to learn more everyday." - Mark O'Shea, 2004
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