The Brown tree snake preys upon birds, lizards, bats and small rodents in its native range. It preys on birds and shrews on Guam.
Due to the availability of prey and lack of predators in introduced habitats such as Guam, they have been known to grow to larger sizes than their normal 1 to 2 meters in length. The longest recorded length of this species is one found on Guam measuring three meters.