If you breed too many generations saying "there don't appear to be any ill-side effects", by the time they do appear then it may be too late for that snakes' family line, as has been stated. Their parents' and their parents parents may all be carrying the same mutant gene, and outbreeding may only half solve the problem... you will then still half have the problem, while thinking you have a genetically diverse line. A little minor inbreeding may not do much damage short-term, or even long term. but for the future generations who inherit these problems, there will be nothing that can be done about it. (such as with pug dogs)
with those bts's there would have been many more snakes have made it into the country in the same way (it would have been cracked down on now with all the new customs laws and such, but i'm sure they couldn't ensure 100% success). And with even one snake making it to the island every ten years, the lines would be sufficiently diversified (If we're going by the "4th/5th generations are ok before you need to outbreed" theory)
IMO snakes (reptiles) because of their slow nature/body/metabolism needs they may evolve slower than other species of creature, and as a result of their not having to create their own energy, one of the side effects may be a slower evolution rate. (my supposition).
I have been told by a number of breeders that reptiles don't have the same problems as mammals with inbreeding. As has been stated by others, it is only those breeders that don't cull unhealthy animals that create the problems.
This is just the opinion of those breeders. They cannot know/prove that snakes don't have the same problems. The apparent defects may appear slower for any reason. e.g. my supposition of slower evolution or some other reason like inbreeding may occur more in wild snakes than other creatures, so they have developed a slower evolution capability to stop from inbreeding themselves to extinction.
Because of the 'cushy' lives of captive snakes even those that appear large and healthy may have been killed and weeded out in the wild because they might never have reached the size they did in captivity if forced to live they way they would have naturally. so the genes of these weaker(but normal appearing) snakes will be passed on to possibly parent weaker lines of snakes. Like i've said, this may not be so crucial short term. but when it happens an overt amount, then the future result could mean trouble.
Also. if everyone is of this opinion ("4th/5th generations are ok"), then what happens when we get the majority of breeders taking this up? There will be a whole lot of breeders breeding their 5th generation snakes with other breeders' 5th generation snakes... Increasing the likelyhood of the genetic defects becoming apparent.. the defects may not become visible until bred with another bloodline who has a similar genetic defect which will suddenly spring up. and even going back to previous generations won't fix it because they will all have the same genetic traits. The whole time this is occurring, they are beleiving they are outbreeding, but down the track, they will all be slightly inbreeding (which has been suggested has occurred in nature (leading to differences for localities and such)).
As said by someone before, best to err on the side of caution. There is no way of eradicating inbreeding of course, but minimising it cannot do any harm. Surely it's not too hard to buy snakes from different sources. Even if you cannot prove that they aren't related, the chances are greater (100% greater) of not having related snakes than if you by a Brother/Sister or Auntie/Uncle and breed them.
There are so many posts that were earlier on that i want to try to dispute and add my opinion to, but i can't think much after writing ALL this (it's like i just sat and wrote an english essay. (btw this thread is awesome, i'm thinking and having to bend my thoughts around these thoughts and opinions (or so it feels).(do i use brackets too much?))).
Teh Monkey