Best quote on the ld50 ever
"The idea of the LD50 (and many similar tests) is that we can accurately extrapolate from non-human species to the human species. But the fact is, we cannot even make crude extrapolations between similar species. We cannot even make reliable extrapolations between different strains of the same species."
The LD50 Test--A Failure of Extreme, but Measurable, Proportions
"The idea of the LD50 (and many similar tests) is that we can accurately extrapolate from non-human species to the human species. But the fact is, we cannot even make crude extrapolations between similar species. We cannot even make reliable extrapolations between different strains of the same species."
The LD50 Test--A Failure of Extreme, but Measurable, Proportions