dont worry, i lost my first python as well..second day i had him as well....
but..dont stress, at night is when you will be most likely to find him, because he'll be ont he move, if u scan around his enclosure at night u may find him, if that faisl u cans et up a few luring techniques involving rats...be inventive!!
ALSO: i remmeber being told when m guy escaped to look at all the skirting boards, and all corners of ur walls, and pretty much all tight high spaces...oh, and in the room he escaped in (if possible) turn of all main heat sources except the one in ur tank, and he may be unger the fridge keeping warm, or anything else thats constantly ona nd generating heat..
i hope this helps!!
i know how stressful it is